Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24446080 | 0.97 | POLB (0.41) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL25581427 | 0.92 | POLB (0.39) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL21675423 | 0.91 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL17485637 | 0.90 | POLB (0.44) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL22592364 | 0.90 | POLB (0.39) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL21693481 | 0.90 | POLB (0.40) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL21254298 | 0.89 | POLB (0.41) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL23543275 | 0.89 | POLB (0.41) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL21693482 | 0.88 | POLB (0.40) | POLBAPEX1HTTTDP1SYK | |
| SCHEMBL23919397 | 0.88 | POLB (0.37) | POLBAPEX1HTTTDP1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219656-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| EP-4194529-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3892706-A2 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2021-10-13 | — | — | EP | disclosed |