Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22592364 | 0.97 | POLB (0.39) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL21254347 | 0.94 | POLB (0.36) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL24446080 | 0.91 | POLB (0.41) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL25581427 | 0.90 | POLB (0.39) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL17485689 | 0.90 | TDP1 (0.39) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL22381392 | 0.88 | TDP1 (0.36) | POLBAPEX1HTTTDP1KDM4E | |
| SCHEMBL21417786 | 0.88 | POLB (0.40) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL23919396 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL22101087 | 0.87 | POLB (0.37) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL24446251 | 0.86 | POLB (0.36) | POLBAPEX1HTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4249570-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-4219656-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2023-08-02 | — | — | EP | disclosed |
| EP-4194529-A1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | Merck Patent GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3892706-A2 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2021-10-13 | — | — | EP | disclosed |