Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500488 | 0.74 | MEN1 (0.44) | MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL14365249 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4518124 | 0.72 | MEN1 (0.42) | MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL19271807 | 0.69 | ALDH1A1 (0.39) | ALDH1A1BRD4BRD2MEN1PKM | |
| SCHEMBL13455118 | 0.67 | BRD4 (0.35) | ALDH1A1BRD4BRD2 | |
| SCHEMBL28318212 | 0.67 | ALDH1A1 (0.36) | ALDH1A1BRD4BRD2KMT2AMAPT | |
| SCHEMBL206785 | 0.67 | MEN1 (0.49) | ALDH1A1BRD4BRD2MEN1PKM | |
| SCHEMBL25157379 | 0.67 | BRD4 (0.40) | ALDH1A1BRD4BRD2MEN1PKM | |
| SCHEMBL6160033 | 0.63 | ALDH1A1 (0.34) | ALDH1A1BRD4BRD2MAPTHSD17B10 | |
| SCHEMBL1440028 | 0.63 | BRD4 (0.43) | ALDH1A1BRD4BRD2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892621-A1 | HALOALLYLAMINE COMPOUNDS AND APPLICATION THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |