Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.33 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372334 | 0.91 | POLRMT (0.49) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL23922543 | 0.89 | POLRMT (0.47) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL22393093 | 0.82 | POLRMT (0.48) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL22372342 | 0.82 | POLRMT (0.50) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL24024298 | 0.81 | POLRMT (0.47) | POLRMTP2RY1TMPRSS2P2RX1P2RX3 | |
| SCHEMBL24120259 | 0.81 | POLRMT (0.51) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL22393569 | 0.81 | POLRMT (0.51) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL22393434 | 0.79 | POLRMT (0.48) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL15678014 | 0.78 | POLRMT (0.49) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 | |
| SCHEMBL24120051 | 0.77 | POLRMT (0.64) | POLRMTP2RY1P2RY2P2RY11TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149049-B2 | Substituted nucleosides, nucleotides and analogs thereof | Janssen Biopharma, Inc. (US) | 2021-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149049-B2 | Substituted nucleosides, nucleotides and analogs thereof | PNP, TYMP, SLC29A1 | POLRMT 48/4885P2RY1 162/4885P2RY2 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.