SCHEMBL23922715

SCHEMBL23922715

COc1ccc(C(C)c2ccc(O)cc2O)cc1C

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.54
MAOB P27338 1/20 0.42
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
CYP3A4 P08684 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
PPARG P37231 1/20 0.39
KMT2A Q03164 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492464 1.00 TYR (0.54) TYRMAOBBCHEACHECYP3A4
SCHEMBL29492256 0.88 TYR (0.54) TYRMAOBBCHEACHECYP3A4
SCHEMBL21830550 0.88 TYR (0.54) TYRMAOBBCHEACHECYP3A4
SCHEMBL29492395 0.88 TYR (0.57) TYRMAOBBCHEACHEPPARG
SCHEMBL21830518 0.88 TYR (0.57) TYRMAOBBCHEACHEPPARG
SCHEMBL21830553 0.83 TYR (0.63) TYRMAOBBCHEACHECYP3A4
SCHEMBL29492396 0.83 TYR (0.63) TYRMAOBBCHEACHECYP3A4
SCHEMBL21830514 0.83 TYR (0.62) TYRACHESLC6A2
SCHEMBL29492429 0.83 TYR (0.62) TYRACHESLC6A2
SCHEMBL21830517 0.82 TYR (0.57) TYRMAOBBCHEACHECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP disclosed
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-09-19 US disclosed
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US disclosed
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-01 US disclosed
EP-4142680-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE Unilever IP Holdings B.V. (NL) 2023-03-08 EP disclosed
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-03-07 US disclosed
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2022-07-07 US disclosed
WO-2021219378-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B.V. (NL) 2021-11-04 WO disclosed
EP-3558246-B1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS UNILEVER IP HOLDINGS B V (NL) 2021-10-20 EP disclosed
CN-110121330-A Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids 荷兰联合利华有限公司 2019-08-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MAOB 3779/4885BCHE 3893/4885
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MAOB 3779/4885BCHE 3893/4885
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE NAA40, CRAT, NQO1 TYR 139/4885MAOB 1782/4885BCHE 1225/4885
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MAOB 3779/4885BCHE 3893/4885
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MAOB 3779/4885BCHE 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.