SCHEMBL23922746

SCHEMBL23922746

COc1cccc(C(C)c2ccc(O)cc2O)c1

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.64
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP3A4 P08684 2/20 0.43
PPARG P37231 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
AOC3 Q16853 2/20 0.42
NR1H4 Q96RI1 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492462 1.00 TYR (0.64) TYRMEN1MAPTKMT2AHSD17B10
SCHEMBL28837569 0.84 TYR (0.46) TYRMEN1KMT2ACYP3A4AOC3
SCHEMBL21830499 0.83 TYR (0.65) TYRMEN1MAPTKMT2ACYP3A4
SCHEMBL29492443 0.83 TYR (0.65) TYRMEN1MAPTKMT2ACYP3A4
SCHEMBL21830515 0.80 TYR (0.70) TYRACHECYP1A2CYP2C19
SCHEMBL29492425 0.80 TYR (0.70) TYRACHECYP1A2CYP2C19
SCHEMBL369337 0.79 TYR (1.00) TYR
SCHEMBL29394395 0.79 TYR (1.00) TYR
SCHEMBL18815425 0.79 TYR (1.00) TYR
SCHEMBL51773 0.78 TYR (0.53) TYRMEN1MAPTKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142680-B1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B V (NL) 2023-10-18 EP disclosed
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-09-19 US disclosed
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-15 US disclosed
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE CONOPCO, INC., D/B/A UNILEVER (US) 2023-06-01 US disclosed
EP-4142680-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE Unilever IP Holdings B.V. (NL) 2023-03-08 EP disclosed
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids CONOPCO, INC. (US) 2023-03-07 US disclosed
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS CONOPCO, INC., D/B/A UNILEVER (US) 2022-07-07 US disclosed
WO-2021219378-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE UNILEVER IP HOLDINGS B.V. (NL) 2021-11-04 WO disclosed
EP-3558246-B1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS UNILEVER IP HOLDINGS B V (NL) 2021-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596586-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MEN1 4391/4885MAPT 1462/4885
US-20220211596-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MEN1 4391/4885MAPT 1462/4885
US-20230165772-A1 STABILIZED COSMETIC COMPOSITIONS WITH N, N'-DI-ACETYL CYSTINE NAA40, CRAT, NQO1 TYR 139/4885MEN1 2447/4885MAPT 2728/4885
US-20230181433-A1 PERSONAL CARE COMPOSITIONS WITH GLUTATHIONE PRECURSOR COMPRISING 4-SUBSTITUTED RESORCINOLS AND AMINO ACIDS GPX1, GPX4, GCLC TYR 6/4885MEN1 4391/4885MAPT 1462/4885
US-11759412-B2 Personal care compositions with glutathione precursor comprising 4-substituted resorcinols and amino acids GPX1, GPX4, GCLC TYR 6/4885MEN1 4391/4885MAPT 1462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.