Succinimide

Succinimide

SCHEMBL23922920

CCC(=O)O.O=C1CCC(=O)N1.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.48
FFAR3 O14843 1/20 0.43
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
CYP2C19 P33261 1/20 0.35
ITGB3 P05106 2/20 0.33
ITGB1 P05556 2/20 0.33
ITGAV P06756 2/20 0.33
ITGB2 P05107 1/20 0.33
ITGA2B P08514 1/20 0.33
ITGA5 P08648 1/20 0.33
ITGB5 P18084 1/20 0.33
ITGAL P20701 1/20 0.33
DDB1 Q16531 3/20 0.31
ITGA4 P13612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL30823560 0.93 CRBN (0.55) CRBNFFAR3KDM4ELMNACYP2C19
Succinimide SCHEMBL2221415 0.93 CRBN (0.55) CRBNFFAR3KDM4ELMNACYP2C19
Succinimide SCHEMBL28348066 0.86 CRBN (0.52) CRBNFFAR3KDM4ELMNACYP2C19
Succinimide SCHEMBL29278585 0.86 CRBN (0.52) CRBNFFAR3KDM4ELMNACYP2C19
Succinimide SCHEMBL20786978 0.86 CRBN (0.58) CRBNKDM4ELMNACYP2C19ITGB3
Succinimide SCHEMBL6153012 0.86 CRBN (0.58) CRBNKDM4ELMNACYP2C19ITGB3
Succinimide SCHEMBL28398892 0.86 FFAR3 (0.50) CRBNFFAR3
Succinic Acid SCHEMBL28918359 0.84 CRBN (0.50) CRBNKDM4ELMNAITGB3ITGB1
Succinic Acid SCHEMBL27856042 0.84 CRBN (0.50) CRBNKDM4ELMNAITGB3ITGB1
Succinimide SCHEMBL29132313 0.84 CRBN (0.55) CRBNKDM4ELMNACYP2C19ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088272-A1 UNDERGLYCOSYLATED KALLIKREIN I, AND POLYETHYLENE GLYCOL MODIFIER THEREOF AND PHARMACEUTICAL USE THEREOF 江苏众红生物工程创药研究院有限公司 2023-05-25 WO claimed
CN-115919755-A Low-concentration hydrogel and preparation method and application thereof 沈阳药科大学 2023-04-07 CN claimed
CN-110201234-B Prostate cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
CN-110251731-B Islet cell microcapsule for tissue engineering and preparation method thereof 山东百多安医疗器械股份有限公司 2021-09-03 CN claimed
CN-112023122-A In-situ injection jelly as well as preparation method and application thereof 北京爱特康医疗科技有限公司 2020-12-04 CN claimed
WO-2023143256-A1 USE OF KININ OR DERIVATIVE THEREOF IN TREATING VCI, PSCI, OR CSVD 江苏众红生物工程创药研究院有限公司 2023-08-03 WO disclosed
WO-2023143246-A1 POLYETHYLENE GLYCOL-MODIFIED FORM OF KININ OR DERIVATIVE THEREOF AND PHARMACEUTICAL USE THEREOF 江苏众红生物工程创药研究院有限公司 2023-08-03 WO disclosed
WO-2023088272-A1 UNDERGLYCOSYLATED KALLIKREIN I, AND POLYETHYLENE GLYCOL MODIFIER THEREOF AND PHARMACEUTICAL USE THEREOF 江苏众红生物工程创药研究院有限公司 2023-05-25 WO disclosed
CN-115919755-A Low-concentration hydrogel and preparation method and application thereof 沈阳药科大学 2023-04-07 CN disclosed
CN-111773178-B Hydrogel lacrimal passage suppository and preparation method thereof 北京诺康达医药科技股份有限公司 2022-11-25 CN disclosed
CN-109963597-B Pegylated endostatin analogs and uses thereof 北京普罗吉生物科技发展有限公司 2022-08-26 CN disclosed
CN-110643057-B Application of polyethylene glycol activated ester in preparation of low-swelling hydrogel and low-swelling hydrogel comprising polyethylene glycol activated ester 赛克赛斯生物科技股份有限公司 2022-05-17 CN disclosed
CN-112023122-B In-situ injection jelly as well as preparation method and application thereof 北京爱特康医疗科技有限公司 2021-03-19 CN disclosed
CN-109077993-B Lacrimal duct slow-release hydrogel implant and preparation method thereof 北京诺康达医药科技股份有限公司 2021-03-16 CN disclosed
CN-112023122-A In-situ injection jelly as well as preparation method and application thereof 北京爱特康医疗科技有限公司 2020-12-04 CN disclosed
CN-107760661-B PEG modifier of medicinal kininogenase and preparation method and application thereof 江苏众红生物工程创药研究院有限公司 2020-10-27 CN disclosed
CN-111773178-A Hydrogel lacrimal passage suppository and preparation method thereof 北京诺康达医药科技股份有限公司 2020-10-16 CN disclosed
CN-111182926-A Particles comprising bilirubin derivatives and metals 株式会社毕丽斯 2020-05-19 CN disclosed
CN-110643057-A Application of polyethylene glycol activated ester in preparation of low-swelling hydrogel and low-swelling hydrogel comprising same 赛克赛斯生物科技股份有限公司 2020-01-03 CN disclosed
CN-103881084-A Phospholipid derivative of branched polyethylene glycol and lipid membrane structure body composed of phospholipid derivative XIAMEN SINOPEG BIOTECH INC 2014-06-25 CN disclosed