Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534707 | 0.78 | MEN1 (0.48) | CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL27714552 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAFAAHCYP1A2CYP2C9 | |
| SCHEMBL2561237 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAFAAHPOLBCNR1 | |
| SCHEMBL30752809 | 0.74 | FAAH (0.36) | SMN1; SMN2LMNAFAAHCYP2C19CYP2D6 | |
| SCHEMBL6664414 | 0.73 | CYP1A2 (0.53) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3635902 | 0.72 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAFAAHCYP1A2CYP2C9 | |
| SCHEMBL8015528 | 0.72 | TSHR (0.48) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL22383428 | 0.72 | TSHR (0.48) | LMNACYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL6262528 | 0.72 | ACP3 (0.41) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL27897428 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAFAAHCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896068-A1 | S1P3 ANTAGONISTS | Teva Pharmaceutical Industries Limited (IL) | 2021-10-20 | — | — | EP | disclosed |