Tert-Butanol

Tert-Butanol

SCHEMBL23923797

CC(C)(C)O.CCC(C)=O

nearest known ligand 0.71

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.71
TDP1 Q9NUW8 3/20 0.71
FFAR3 O14843 1/20 0.41
TSHR P16473 2/20 0.39
TRPA1 O75762 1/20 0.39
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
LMNA P02545 3/20 0.33
SLC15A2 Q16348 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CES2 O00748 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butanol SCHEMBL28779762 0.97 ALDH1A1 (0.67) ALDH1A1TDP1FFAR3TSHRTRPA1
Tert-Butanol SCHEMBL11318776 0.97 ALDH1A1 (0.67) ALDH1A1TDP1FFAR3TSHRTRPA1
Tert-Butanol SCHEMBL28779760 0.94 ALDH1A1 (0.62) ALDH1A1TDP1FFAR3TSHRTRPA1
Butanone SCHEMBL28350067 0.85
Butanone SCHEMBL1039820 0.84 ALDH1A1 (1.00) ALDH1A1TDP1FFAR3TSHRTRPA1
Butanone SCHEMBL1310 0.84
Butanone SCHEMBL1510153 0.84
Butanone SCHEMBL8379087 0.84 ALDH1A1 (1.00) ALDH1A1TDP1FFAR3TSHRTRPA1
Butanone SCHEMBL6307020 0.84 ALDH1A1 (0.59) ALDH1A1TDP1FFAR3TSHRTRPA1
Butanone SCHEMBL1445496 0.82 ALDH1A1 (0.56) ALDH1A1TDP1FFAR3TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210324169-A1 ENGINEERING A POROUS CONDUCTIVE PEDOT:PSS-DVS SCAFFOLD FOR MICROBIAL FUEL CELL AIR CATHODES NORTHEASTERN UNIVERSITY 2021-10-21 US disclosed
CN-103533835-B S1P modulators 比奥根MA公司 2016-08-24 CN disclosed
CN-104684560-A Compounds that are S1P modulating agents and/or ATX modulating agents BIOGEN IDEC INC 2015-06-03 CN disclosed
CN-103533835-A S1P modulators BIOGEN IDEC INC 2014-01-22 CN disclosed