Uridine_Diphosphate

Uridine_Diphosphate

SCHEMBL23923917

O=CC(O)C(O)C(O)C(O)CO.O=P(O)(O)O.O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.68

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Uridine_Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 8/20 0.68
P2RY2 P41231 12/20 0.67
P2RY4 P51582 7/20 0.67
P2RY14 Q15391 6/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine_Diphosphate SCHEMBL667655 0.99 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL4311732 0.99 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL454080 0.99 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL27785901 0.99 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL20553195 0.99 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL8740673 0.98 P2RY6 (0.68) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL28303416 0.98 P2RY6 (0.68) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL27780277 0.98 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL4295328 0.98 P2RY6 (0.69) P2RY6P2RY2P2RY4P2RY14
Uridine_Diphosphate SCHEMBL27463201 0.96 P2RY6 (0.65) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210324345-A1 Recombinant Microorganism for Producing 2,3-Butanediol and a Method of Production of 2,3-Butanediol CPC CORPORATION, TAIWAN (TW) 2021-10-21 US claimed
US-20210324345-A1 Recombinant Microorganism for Producing 2,3-Butanediol and a Method of Production of 2,3-Butanediol CPC CORPORATION, TAIWAN (TW) 2021-10-21 US disclosed
US-20210324345-A1 Recombinant Microorganism for Producing 2,3-Butanediol and a Method of Production of 2,3-Butanediol CPC CORPORATION, TAIWAN (TW) 2021-10-21 US disclosed
CN-102154190-B Engineering escherichia coli capable of efficiently producing hyaluronic acid and preparation method thereof YUNNAN MICROBIOLOGY FERMENT ENGINEERING RES CT CO LTD 2012-09-05 CN disclosed
CN-102154190-A Engineering escherichia coli capable of efficiently producing hyaluronic acid and preparation method thereof YUNNAN MICROBIOLOGY FERMENT ENGINEERING RES CT CO LTD 2011-08-17 CN disclosed