Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924041 | 0.93 | PIK3CD (0.51) | GRM5PIK3CDTGFBR1PARP1DHODH | |
| SCHEMBL2487987 | 0.78 | PIK3CD (0.52) | GRM5PIK3CDPARP1KEAP1NFE2L2 | |
| SCHEMBL31227380 | 0.78 | PIK3CD (0.52) | GRM5PIK3CDPARP1KEAP1NFE2L2 | |
| SCHEMBL2943452 | 0.78 | GRM5 (0.54) | GRM5PARP1DHODHPARP2KEAP1 | |
| SCHEMBL31249984 | 0.76 | GRM5 (0.64) | GRM5TGFBR1PARP1DHODHPARP2 | |
| SCHEMBL29506339 | 0.76 | GRM5 (0.64) | GRM5TGFBR1PARP1DHODHPARP2 | |
| SCHEMBL997865 | 0.76 | GRM5 (0.64) | GRM5TGFBR1PARP1DHODHPARP2 | |
| SCHEMBL31249988 | 0.76 | GRM5 (0.64) | GRM5TGFBR1PARP1DHODHPARP2 | |
| Hydrochloric Acid SCHEMBL28843225 | 0.75 | GRM5 (0.62) | GRM5TGFBR1PARP1DHODHPARP2 | |
| Hydrochloric Acid SCHEMBL30105351 | 0.75 | GRM5 (0.62) | GRM5TGFBR1PARP1DHODHPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322404-A1 | FGFR REGULATION FOR THE TREATMENT OF VIRAL INFECTIONS | ETH ZURICH (CH) | 2021-10-21 | — | — | US | disclosed |