Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.64 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31249988 | 1.00 | GRM5 (0.64) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL31249984 | 1.00 | GRM5 (0.64) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL29506339 | 1.00 | GRM5 (0.64) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| Hydrochloric Acid SCHEMBL28843225 | 0.98 | GRM5 (0.62) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL29184190 | 0.98 | GRM5 (0.62) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| Hydrochloric Acid SCHEMBL30105351 | 0.98 | GRM5 (0.62) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL28555590 | 0.93 | GRM5 (0.61) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| Maleic Acid SCHEMBL25297964 | 0.91 | GRM5 (0.56) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| Pyrrole SCHEMBL28244114 | 0.91 | GRM5 (0.56) | GRM5BCAT2CSNK1A1TYRO3DYRK1B | |
| SCHEMBL2012719 | 0.85 | GRM5 (0.53) | GRM5BCAT2CSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046117-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2023-03-30 | — | — | WO | claimed |
| CN-115215794-A | N-2-pyridylbenzimine derivative and preparation method and application thereof | 江苏海洋大学 | 2022-10-21 | — | — | CN | claimed |
| CN-109608454-B | Novel method for synthesizing 6H-pyridine [1,2-c ] quinazoline-6-ketone compound | 河南师范大学 | 2022-09-13 | — | — | CN | claimed |
| CN-111362966-B | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-106831285-B | Method for converting amide and urea into ester | 湖北科技学院 | 2020-08-11 | — | — | CN | claimed |
| US-10612019-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-04-07 | — | — | US | claimed |
| US-10609930-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-04-07 | — | — | US | claimed |
| US-10568328-B2 | Methods and compositions for weed control | MONSANTO TECHNOLOGY LLC (US) | 2020-02-25 | — | — | US | claimed |
| EP-3601264-A1 | BRUTON'S TYROSINE KINASE INHIBITORS | Liao, Xibin (US) | 2020-02-05 | — | — | EP | claimed |
| EP-3604535-A2 | METHODS AND COMPOSITIONS FOR WEED CONTROL | Monsanto Technology LLC (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | claimed |
| EP-2734522-A1 | 4 - IMIDAZOPYRIDAZIN- 1 -YL-BENZAMIDES AND 4 - IMIDAZOTRIAZIN- 1 - YL - BENZAMIDES AS BTK- INHIBITORS | Merck Sharp & Dohme B.V. (NL) | 2014-05-28 | — | — | EP | claimed |
| CN-103608350-A | Triazolopyridine compounds | BAYER IP GMBH | 2014-02-26 | — | — | CN | claimed |
| WO-2013010868-A1 | 4 - IMIDAZOPYRIDAZIN- 1 -YL-BENZAMIDES AND 4 - IMIDAZOTRIAZIN- 1 - YL - BENZAMIDES AS BTK- INHIBITORS | MSD OSS B.V. (NL) | 2013-01-24 | — | — | WO | claimed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| CN-101400657-A | Polycyclic cinnamamide derivative | ESAI R & D MAN CO LTD (JP) | 2009-04-01 | — | — | CN | claimed |
| EP-1140087-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | claimed |
| EP-1140087-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035454-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | claimed |
| WO-1993016053-A1 | NOVEL BISTETRAZOL DERIVATIVES HAVING AN ANTIALLERGIC AND CYTOPROTECTIVE ACTIVITY | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1993-08-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10609930-B2 | Methods and compositions for weed control | AS3MT, NOTUM, POLR1C | GRM5 2092/4885BCAT2 4101/4885CSNK1A1 4518/4885 |
| US-10612019-B2 | Methods and compositions for weed control | NOTUM, LOXL3, CXXC5 | GRM5 313/4885BCAT2 2856/4885CSNK1A1 2584/4885 |
| US-10568328-B2 | Methods and compositions for weed control | CYC1, PRDX5, CYCS | GRM5 1876/4885BCAT2 587/4885CSNK1A1 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.