Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475203 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDE4BKMT2AMEN1 | |
| SCHEMBL20475191 | 0.89 | PDE4B (0.51) | ALDH1A1L3MBTL1PDE4BSLC6A2SLC6A4 | |
| SCHEMBL29585724 | 0.87 | GAA (0.49) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL18586579 | 0.87 | GAA (0.49) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL29585798 | 0.87 | GAA (0.49) | ALDH1A1L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL6309437 | 0.84 | PDE4B (0.62) | ALDH1A1L3MBTL1PDE4B | |
| SCHEMBL23924353 | 0.84 | PDE4B (0.62) | ALDH1A1L3MBTL1PDE4B | |
| SCHEMBL23941883 | 0.84 | PDE4B (0.62) | ALDH1A1L3MBTL1PDE4B | |
| SCHEMBL20475209 | 0.84 | PDE4A (0.51) | ALDH1A1L3MBTL1PDE4BKMT2AMEN1 | |
| SCHEMBL19559527 | 0.84 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S R L (IT) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | ALDH1A1 2328/4885L3MBTL1 1169/4885PDE4B 2677/4885 |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | ALDH1A1 2328/4885L3MBTL1 1169/4885PDE4B 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.