Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924378 | 1.00 | KMT2A (0.53) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23951374 | 0.88 | KMT2A (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924317 | 0.83 | ALDH1A1 (0.53) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23951604 | 0.83 | ALDH1A1 (0.53) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924172 | 0.82 | TRPV1 (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924282 | 0.82 | TRPV1 (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924118 | 0.82 | TRPV1 (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924170 | 0.82 | TRPV1 (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924493 | 0.82 | TRPV1 (0.47) | KMT2AHTTMEN1BLMMAPK1 | |
| SCHEMBL23924011 | 0.82 | KMT2A (0.48) | KMT2AHTTMEN1BLMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S R L (IT) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | KMT2A 1332/4885HTT 1219/4885MEN1 4081/4885 |
| US-20210323942-A1 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | KMT2A 1332/4885HTT 1219/4885MEN1 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.