Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BHMT | Q93088 | 10/20 | 0.36 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL3091904 | 1.00 | MEN1 (0.43) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL4402781 | 1.00 | MEN1 (0.43) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL28765103 | 0.95 | MEN1 (0.41) | MEN1KMT2ABHMTBHMT2LMNA | |
| Glutamic Acid SCHEMBL6740018 | 0.95 | MEN1 (0.41) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL4275752 | 0.95 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL23924535 | 0.95 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL4275749 | 0.95 | MEN1 (0.47) | MEN1KMT2ABHMTBHMT2LMNA | |
| D-Glutamate SCHEMBL20213749 | 0.91 | GRM8 (0.44) | MEN1KMT2ABHMTBHMT2LMNA | |
| Racemethionine SCHEMBL9784232 | 0.91 | MEN1 (0.44) | MEN1KMT2ABHMTBHMT2LMNA | |
| Methionine SCHEMBL6248021 | 0.91 | MEN1 (0.44) | MEN1KMT2ABHMTBHMT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894608-A | Methionine synthesized collagen polypeptide, tripeptide monomer molecule and preparation method thereof | 杭州协合医疗用品有限公司 | 2023-04-04 | — | — | CN | claimed |
| US-20210324027-A1 | MODIFIED INTERLEUKIN-7 PROTEINS AND USES THEREOF | GENEXINE, INC. (KR) | 2021-10-21 | — | — | US | claimed |
| CN-115894608-A | Methionine synthesized collagen polypeptide, tripeptide monomer molecule and preparation method thereof | 杭州协合医疗用品有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-20210324027-A1 | MODIFIED INTERLEUKIN-7 PROTEINS AND USES THEREOF | GENEXINE, INC. (KR) | 2021-10-21 | — | — | US | disclosed |
| CN-1917869-A | Composition and method for use in cartilage affecting conditions | HILLS PET NUTRITION INC (US) | 2007-02-21 | — | — | CN | disclosed |