Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27176596 | 0.87 | CA1 (0.44) | CA1CA2XDHNT5EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28697827 | 0.87 | CA1 (0.43) | CA1CA2XDHALDH1A1MAPT | |
| SCHEMBL28977673 | 0.85 | CA1 (0.41) | CA1CA2XDHALDH1A1MAPT | |
| SCHEMBL11938826 | 0.85 | CA1 (0.42) | CA1CA2XDHNT5EALDH1A1 | |
| SCHEMBL534293 | 0.85 | CA1 (0.41) | CA1CA2XDHALDH1A1MAPT | |
| SCHEMBL534295 | 0.85 | CA1 (0.39) | CA1CA2XDHNT5EALDH1A1 | |
| SCHEMBL23931330 | 0.82 | CA1 (0.42) | CA1CA2XDHALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL19810858 | 0.82 | CA1 (0.46) | CA1CA2MAPTTHRB | |
| Hydrochloric Acid SCHEMBL28977617 | 0.82 | CA1 (0.41) | CA1CA2NT5EMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL16894026 | 0.82 | CA1 (0.52) | CA1CA2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209120-A1 | PROCESSING IN HUMID AIR OF EFFICIENT PEROVSKITE SOLAR CELLS BASED ON POLYMERIZABLE IONIC LIQUIDS AND SALTS | TOYOTA MOTOR EUROPE (BE) | 2021-10-21 | — | — | WO | claimed |
| CN-110224069-B | Perovskite solar cell with waterproof function and preparation method thereof | 天合光能股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| WO-2021209120-A1 | PROCESSING IN HUMID AIR OF EFFICIENT PEROVSKITE SOLAR CELLS BASED ON POLYMERIZABLE IONIC LIQUIDS AND SALTS | TOYOTA MOTOR EUROPE (BE) | 2021-10-21 | — | — | WO | disclosed |