Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 1/20 | 1.00 |
| ▸ | CHRNB4 | P30926 | 1/20 | 1.00 |
| ▸ | CHRNA3 | P32297 | 1/20 | 1.00 |
| ▸ | CHRNA4 | P43681 | 1/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.75 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.75 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ibogaine SCHEMBL31738807 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL32677903 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL10035903 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL14964144 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL14664380 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL32677904 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL113571 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL4400751 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL21333266 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 | |
| Ibogaine SCHEMBL31166257 | 1.00 | SLC6A4 (1.00) | SLC6A4SIGMAR1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-02 | — | — | US | disclosed |
| EP-4135712-A1 | TRANSDERMAL MICRO-DOSING DELIVERY OF PSYCHEDELICS DERIVATIVES | Pike Therapeutics, Inc. (CA) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021209815-A1 | TRANSDERMAL MICRO-DOSING DELIVERY OF PSYCHEDELICS DERIVATIVES | PIKE THERAPEUTICS, INC. (CA) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | CHRNA3, CHRNB3, CHRNA4 | SLC6A4 76/4885SIGMAR1 201/4885CHRNB2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.