Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.60 |
| ▸ | TSHR | P16473 | 11/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | USP2 | O75604 | 6/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17149372 | 0.81 | KDM4C (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL30711679 | 0.81 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL20237993 | 0.81 | CYP1A2 (0.67) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL28091678 | 0.81 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL16343541 | 0.81 | KDM4C (0.64) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL31042791 | 0.81 | KDM4C (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL28320773 | 0.81 | KDM4C (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL1690631 | 0.80 | CYP1A2 (0.68) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL31275112 | 0.79 | KDM4C (0.57) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR | |
| SCHEMBL21174364 | 0.78 | KDM4C (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295119-A1 | SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | GOSSAMER BIO SERVICES INC (US) | 2023-09-21 | — | — | US | disclosed |
| EP-4136073-A1 | SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | Gossamer Bio Services, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115702145-A | Substituted pyridines for the treatment of inflammatory diseases | 戈萨默生物服务公司 | 2023-02-14 | — | — | CN | disclosed |
| WO-2021211741-A1 | SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | GOSSAMER BIO SERVICES, INC. (US) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295119-A1 | SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATORY DISEASES | IRAK3, TYK2, IRAK2 | CYP1A2 490/4885CYP3A4 1364/4885CYP2D6 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.