Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836815 | 0.70 | HDAC1 (0.37) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL13495858 | 0.69 | AKR1B1 (0.44) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL20734708 | 0.68 | AKR1B1 (0.45) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL16112476 | 0.67 | AKR1B1 (0.36) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL9293486 | 0.64 | KDM4E (0.39) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL11124180 | 0.64 | AKR1B1 (0.40) | ALDH1A1HPGDAKR1B1 | |
| SCHEMBL32673162 | 0.62 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL11477205 | 0.62 | PSMB5 (0.43) | AKR1B1 | |
| SCHEMBL2331538 | 0.61 | GRIA1 (0.38) | KDM4EALDH1A1HPGDAKR1B1 | |
| SCHEMBL6836726 | 0.61 | KDM4E (0.53) | KDM4EALDH1A1HPGDAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2023-04-20 | — | — | US | claimed |
| WO-2021211982-A2 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2021-10-21 | — | — | WO | claimed |
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021211982-A2 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2021-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | CYP2B6, TYR, CYP2D6 | KDM4E 1082/4885ALDH1A1 88/4885HPGD 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.