SCHEMBL16112476

SCHEMBL16112476

Cc1nccc2c1OC(=O)C2

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.36
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19152990 0.84 ALDH2 (0.36) PDE3BPDE3AKDM4EHPGD
SCHEMBL13495858 0.69 AKR1B1 (0.44) AKR1B1KDM4EALDH1A1HPGD
SCHEMBL11242915 0.68 AAK1 (0.32) PDE3BPDE3A
SCHEMBL20734708 0.67 AKR1B1 (0.45) AKR1B1KDM4EALDH1A1HPGD
SCHEMBL25273228 0.64 DAO (0.34)
SCHEMBL26195441 0.63 RECQL (0.33)
SCHEMBL19886739 0.63 P2RX7 (0.30)
SCHEMBL14660842 0.63 PSMB5 (0.44) PDE3BPDE3A
SCHEMBL19153853 0.63 NOS3 (0.35)
SCHEMBL30048869 0.63 KDM4E (0.44) PDE3BPDE3AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978314-A1 COMPOSITIONS AND METHODS FOR ENHANCING PLANT GROWTH Novozymes Bio AG A/S (DK) 2016-02-03 EP disclosed
WO-2014160826-A1 COMPOSITIONS AND METHODS FOR ENHANCING PLANT GROWTH NOVOZYMES BIOAG A/S (DK) 2014-10-02 WO disclosed