SCHEMBL23926162

SCHEMBL23926162

C=CC(=O)N1CCN(C(=O)CN2CCc3ccccc3C2c2ccccc2C)CC1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 6/20 0.45
PRCP P42785 3/20 0.43
HDAC1 Q13547 5/20 0.39
HDAC3 O15379 4/20 0.39
HDAC2 Q92769 4/20 0.39
NCOR2 Q9Y618 4/20 0.39
ACHE P22303 1/20 0.39
KRAS P01116 5/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763681 1.00 HDAC8 (0.45) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23947733 0.88 HDAC8 (0.46) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23948067 0.88 DRD1 (0.46) HDAC8HDAC1HDAC3HDAC2NCOR2
SCHEMBL23948066 0.88 MTNR1B (0.46) HDAC8HDAC1HDAC3HDAC2NCOR2
SCHEMBL23948064 0.87 HDAC8 (0.45) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23948063 0.87 HDAC8 (0.45) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23947732 0.87 HDAC8 (0.61) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23947736 0.86 HCRTR1 (0.44) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23948065 0.85 HDAC8 (0.43) HDAC8PRCPHDAC1HDAC3HDAC2
SCHEMBL23948095 0.84 HDAC8 (0.46) HDAC8PRCPHDAC1HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4135698-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS The Trustees of Indiana University (US) 2023-02-22 EP disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 US disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 WO disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI HDAC8 988/4885PRCP 1119/4885HDAC1 935/4885
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI HDAC8 988/4885PRCP 1119/4885HDAC1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.