SCHEMBL23926453

SCHEMBL23926453

OCC[N+]1(Cc2ccc(I)cc2)CCOCC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 4/20 0.33
EPAS1 Q99814 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL20604348 0.98 SMN1; SMN2 (0.37) SMN1; SMN2HIF1AEPAS1
SCHEMBL23926449 0.85 CHRNA7 (0.35)
Bromide SCHEMBL20604280 0.83 CHRNA7 (0.34)
Water SCHEMBL1702603 0.82 SMN1; SMN2 (0.44) SMN1; SMN2HIF1A
SCHEMBL23926429 0.75 SMN1; SMN2 (0.39) SMN1; SMN2
Hydrochloric Acid SCHEMBL20604500 0.74 SMN1; SMN2 (0.38) SMN1; SMN2
Bromide SCHEMBL20604499 0.74 SMN1; SMN2 (0.41) SMN1; SMN2
SCHEMBL4907261 0.72 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL16883445 0.72 ALDH1A1 (0.34) SMN1; SMN2
Hydrochloric Acid SCHEMBL30804526 0.70 SMN1; SMN2 (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423441-B1 IODINATED ANALOGS OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS UNIV PALACKEHO (CZ) 2021-10-27 EP claimed