Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990696 | 0.71 | — | — | |
| SCHEMBL18797776 | 0.67 | PIK3CD (0.41) | DPP4DPP8DPP9RIPK1 | |
| SCHEMBL19990608 | 0.65 | ATM (0.31) | — | |
| SCHEMBL21981531 | 0.65 | ATM (0.31) | — | |
| SCHEMBL23927099 | 0.65 | CYP1A2 (0.36) | RIPK1 | |
| SCHEMBL19990787 | 0.64 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL19990731 | 0.61 | ATM (0.34) | DPP4DPP8DPP9 | |
| SCHEMBL19990704 | 0.61 | ATM (0.34) | DPP4DPP8DPP9 | |
| SCHEMBL28695065 | 0.59 | NR1H2 (0.39) | RIPK1 | |
| SCHEMBL746205 | 0.59 | ATM (0.48) | DPP4DPP8DPP9RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-B1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | NOVARTIS AG (CH) | 2021-10-27 | — | — | EP | disclosed |