SCHEMBL23927272 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ABL1	P00519	13/20	0.51

▸	SRC	P12931	3/20	0.51

▸	SIK2	Q9H0K1	13/20	0.48

▸	SIK3	Q9Y2K2	13/20	0.48

▸	SIK1	P57059	11/20	0.48

▸	BCR	P11274	2/20	0.47

▸	HDAC1	Q13547	2/20	0.47

▸	PKMYT1	Q99640	1/20	0.46

▸	LCK	P06239	2/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23927260	0.84	SIK2 (0.59)	ABL1SRCSIK2SIK3SIK1
SCHEMBL23927252	0.81	SIK2 (0.61)	ABL1SRCSIK2SIK3SIK1
SCHEMBL23987729	0.76	SIK2 (0.48)	ABL1SRCSIK2SIK3SIK1
SCHEMBL23927240	0.75	SIK2 (0.62)	ABL1SRCSIK2SIK3SIK1
SCHEMBL23987735	0.69	SIK2 (0.45)	ABL1SRCSIK2SIK3SIK1
SCHEMBL23927238	0.69	ABL1 (0.71)	ABL1SRCSIK2SIK3SIK1
SCHEMBL19436378	0.68	ABL1 (0.66)	ABL1SRCSIK2SIK3SIK1
SCHEMBL1147163	0.67	ABL1 (1.00)	ABL1SRCSIK2SIK3SIK1
SCHEMBL29618220	0.67	ABL1 (1.00)	ABL1SRCSIK2SIK3SIK1
SCHEMBL29352726	0.67	ABL1 (1.00)	ABL1SRCSIK2SIK3SIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3901151-A1	HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF	iOmx Therapeutics AG (DE)	2021-10-27	—	—	EP	disclosed