Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.62 |
| ▸ | IKBKB | O14920 | 4/20 | 0.62 |
| ▸ | RARG | P13631 | 9/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17847414 | 0.90 | RARA (0.73) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL19639489 | 0.86 | RARA (0.62) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL23927744 | 0.86 | RARA (0.61) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL5888172 | 0.86 | RARA (0.77) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL17847378 | 0.84 | RARA (0.66) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL17847393 | 0.83 | RARA (0.74) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8690793 | 0.83 | RARA (0.61) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL19639432 | 0.83 | RARA (0.67) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8426173 | 0.83 | RARA (0.70) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8690758 | 0.82 | RARA (0.65) | RARAIKBKBRARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233806-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RES & DEV (FR) | 2021-10-27 | — | — | EP | disclosed |