Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940314 | 1.00 | FFAR1 (0.47) | FFAR1FFAR4SCN9AEDNRBEDNRA | |
| SCHEMBL29423913 | 0.90 | FFAR1 (0.43) | FFAR1FFAR4SCN9ASCN3A | |
| SCHEMBL16855673 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4ALKBH1 | |
| SCHEMBL29423892 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4ALKBH1 | |
| SCHEMBL16829648 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4ALKBH1 | |
| SCHEMBL16846007 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4ALKBH1 | |
| SCHEMBL16845954 | 0.83 | FFAR1 (0.42) | FFAR1FFAR4EDNRBEDNRA | |
| SCHEMBL23952766 | 0.83 | FFAR1 (0.42) | FFAR1FFAR4EDNRBEDNRA | |
| SCHEMBL29423947 | 0.79 | FFAR1 (0.46) | FFAR1FFAR4ALKBH1 | |
| SCHEMBL16846006 | 0.79 | FFAR1 (0.46) | FFAR1FFAR4ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082786-B1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME (US) | 2021-10-27 | — | — | EP | disclosed |