2-Methoxyethanol

2-Methoxyethanol

SCHEMBL23928708

C=CC(=O)OCC(C)(C)C.COCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
THRB P10828 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL230725 0.87 ALDH1A1 (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL285659 0.85 ALDH1A1 (0.59) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL11107036 0.83 ALDH1A1 (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
2-Methoxyethanol SCHEMBL11221302 0.82 TSHR (0.69) TSHRALDH1A1TP53HIF1ACYP3A4
Hydrochloric Acid SCHEMBL28271407 0.81 ALDH1A1 (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
Dimethylamine SCHEMBL6114524 0.80 ALDH1A1 (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5282067 0.78 TSHR (0.76) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL7736873 0.78 ALDH1A1 (0.53) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL28305502 0.78 ALDH1A1 (0.49) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL27532093 0.77 TSHR (0.56) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112601669-B Tire with a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative 米其林集团总公司 2022-12-16 CN disclosed
CN-115066475-A Addition curable silicone adhesive composition 迈图高新材料公司 2022-09-16 CN disclosed
US-20210332168-A1 TIRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-28 US disclosed
CN-112601669-A Tire with a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative 米其林集团总公司 2021-04-02 CN disclosed