⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621239 | 0.79 | — | — | |
| SCHEMBL17541003 | 0.77 | — | — | |
| SCHEMBL21621369 | 0.77 | BAZ2B (0.38) | — | |
| SCHEMBL15158971 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL136187 | 0.72 | CYP2C9 (0.44) | — | |
| SCHEMBL17484922 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL13838792 | 0.69 | HSD11B1 (0.55) | — | |
| SCHEMBL21815530 | 0.68 | SLC1A3 (0.50) | — | |
| SCHEMBL24966202 | 0.68 | BRD4 (0.48) | — | |
| SCHEMBL17813609 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137765-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2026-05-21 | — | — | US | disclosed |
| US-12527854-B2 | Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof | INSTITUT CURIE (FR) | 2026-01-20 | — | — | US | disclosed |
| EP-3856164-B1 | MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS | ACHILLION PHARMACEUTICALS INC (US) | 2024-08-07 | — | — | EP | disclosed |
| US-11807627-B2 | Morphic forms of complement factor D inhibitors | Achillon Pharmaceuticals, Inc. (US) | 2023-11-07 | — | — | US | disclosed |
| US-20220233673-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2022-07-28 | — | — | US | disclosed |
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| US-20210332026-A1 | MORPHIC FORMS OF COMPLEMENT FACTOR D INHIBITORS | ACHILLION PHARMACEUTICALS, INC. (US) | 2021-10-28 | — | — | US | disclosed |
| CN-112996497-A | Morphic forms of complement factor D inhibitors | 艾其林医药公司 | 2021-06-18 | — | — | CN | disclosed |