SCHEMBL23928727

SCHEMBL23928727

N=C(N)NCCCCNP(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
ALB P02768 1/20 0.33
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.32
MMP2 P08253 1/20 0.31
SPHK1 Q9NYA1 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Agmatine SCHEMBL28651766 0.79 ALOX15 (0.46) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL31511876 0.79 ALOX15 (0.42) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Agmatine SCHEMBL4417794 0.79 ALOX15 (0.46) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Arcaine SCHEMBL303546 0.79 MEN1 (0.62) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Phosphoric Acid SCHEMBL28436026 0.77 ALOX15 (0.43) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
Phosphoric Acid SCHEMBL29118306 0.77 ALOX15 (0.43) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL3069140 0.77 SMN1; SMN2 (0.67) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL3072659 0.77 SMN1; SMN2 (0.67) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL10728151 0.77 SMN1; SMN2 (0.67) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL11882788 0.77 SMN1; SMN2 (0.67) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US claimed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP claimed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
US-20230183746-A1 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2023-06-15 US disclosed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP disclosed
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY SIXFOLD BIOSCIENCE LTD (GB) 2022-11-24 US disclosed
EP-4022058-A2 COMPOSITIONS FOR TRANSFER OF CARGO TO CELLS Sixfold Bioscience Ltd. (GB) 2022-07-06 EP disclosed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 US disclosed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 WO disclosed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-20220370635-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN ALOX15 2891/4885MEN1 890/4885CYP1A2 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.