Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805188 | 0.79 | ITGB3 (0.39) | ITGB3ITGA2BCPA1GRIK1GRIK2 | |
| SCHEMBL4075575 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BCPA1GRIK1GRIK2 | |
| SCHEMBL1853265 | 0.75 | ITGB3 (0.36) | ITGB3ITGA2BCPA1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL28406114 | 0.73 | ITGB3 (0.39) | ITGB3ITGA2BCPA1GRIK1GRIK2 | |
| SCHEMBL18916775 | 0.73 | ITGB3 (0.39) | ITGB3ITGA2BCPA1GRIK1GRIK2 | |
| SCHEMBL11897680 | 0.72 | ITGB3 (0.35) | ITGB3ITGA2BCPA1 | |
| SCHEMBL6430077 | 0.70 | ABCC4 (0.39) | CPA1GRIK1GRIK2ABCC4MAPT | |
| SCHEMBL13347365 | 0.70 | ABCC4 (0.39) | CPA1GRIK1GRIK2ABCC4MAPT | |
| Sulfuric Acid SCHEMBL1848485 | 0.70 | ITGB3 (0.34) | ITGB3ITGA2BCPA1 | |
| SCHEMBL24508704 | 0.70 | SLC22A6 (0.35) | SLC22A6TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220226434-A1 | METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-07-21 | — | — | US | disclosed |
| CN-114206911-A | Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds | 加利福尼亚大学董事会 | 2022-03-18 | — | — | CN | disclosed |
| US-20210371463-A1 | Modified Netrin-1 Peptides and Compositions for Cardioprotection | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-12-02 | — | — | US | disclosed |
| US-20210332083-A1 | Netrin-1 Compounds and Compositions Thereof for Treating Pulmonary Hypertension | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | disclosed |
| CN-113412116-A | Modified axon growth-attractant factor-1 peptides and compositions for cardioprotection | 加利福尼亚大学董事会 | 2021-09-17 | — | — | CN | disclosed |
| CN-113286805-A | Axon growth-inducing factor-1 compounds and compositions thereof for the treatment of pulmonary hypertension | 加利福尼亚大学董事会 | 2021-08-20 | — | — | CN | disclosed |