Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30211141 | 1.00 | KMT2A (0.43) | KMT2AMAPK1MEN1MAPTHTT | |
| SCHEMBL23929162 | 1.00 | KMT2A (0.43) | KMT2AMAPK1MEN1MAPTHTT | |
| SCHEMBL19061633 | 0.88 | NLRP3 (0.49) | MAPK1NLRP3KDM4ECYP1A2CYP3A4 | |
| SCHEMBL19061767 | 0.88 | NLRP3 (0.49) | MAPK1NLRP3KDM4ECYP1A2CYP3A4 | |
| SCHEMBL23929176 | 0.86 | HIF1A (0.48) | MAPK1CYP3A4ALOX15HIF1AOPRM1 | |
| SCHEMBL19061658 | 0.86 | HIF1A (0.48) | MAPK1CYP3A4ALOX15HIF1AOPRM1 | |
| SCHEMBL23929216 | 0.85 | KDM4E (0.42) | KMT2AMAPK1MEN1MAPTKDM4E | |
| SCHEMBL19061898 | 0.85 | KDM4E (0.42) | KMT2AMAPK1MEN1MAPTKDM4E | |
| SCHEMBL30211116 | 0.85 | KDM4E (0.42) | KMT2AMAPK1MEN1MAPTKDM4E | |
| SCHEMBL23929213 | 0.85 | KDM4E (0.42) | KMT2AMAPK1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667275-B | Boron-containing compounds and uses thereof | 南京再明医药有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115667275-A | Boron-containing compounds and their use | 先声药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021213358-A1 | BORON-CONTAINING COMPOUNDS AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021213358-A1 | BORON-CONTAINING COMPOUNDS AND APPLICATION THEREOF | 江苏先声药业有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |