Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3635864 | 0.87 | — | — | |
| Formamide SCHEMBL4415470 | 0.85 | HPGD (0.35) | HPGDGAACYP1A2ALDH1A1CXCR4 | |
| Ammonia Solution, Strong SCHEMBL28544624 | 0.84 | CYP1A2 (0.43) | HPGDGAARECQLCYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3631298 | 0.84 | CYP1A2 (0.39) | HPGDGAACYP1A2ALDH1A1KDM4E | |
| Bromide SCHEMBL23929285 | 0.84 | CYP1A2 (0.39) | HPGDGAACYP1A2ALDH1A1CXCR4 | |
| Hydrochloric Acid SCHEMBL4706089 | 0.84 | CYP1A2 (0.39) | HPGDGAACYP1A2ALDH1A1KDM4E | |
| SCHEMBL2442076 | 0.84 | — | — | |
| SCHEMBL5242776 | 0.84 | — | — | |
| SCHEMBL29028773 | 0.84 | CYP1A2 (0.41) | HPGDGAACYP1A2ALDH1A1 | |
| SCHEMBL223265 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168009-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | Hangzhou DAC Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |