Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.57 |
| ▸ | EGLN2 | Q96KS0 | 17/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14942062 | 0.90 | EGLN1 (0.55) | EGLN1EGLN2 | |
| SCHEMBL15268696 | 0.88 | EGLN1 (0.55) | EGLN1EGLN2 | |
| SCHEMBL5140999 | 0.86 | EGLN2 (0.57) | EGLN1EGLN2 | |
| SCHEMBL22493050 | 0.86 | EGLN1 (0.51) | EGLN1EGLN2 | |
| SCHEMBL1115849 | 0.85 | EGLN1 (0.77) | EGLN1EGLN2 | |
| Hydrochloric Acid SCHEMBL22588812 | 0.85 | EGLN1 (0.53) | EGLN1EGLN2 | |
| SCHEMBL6059867 | 0.84 | EGLN1 (0.52) | EGLN1EGLN2 | |
| SCHEMBL6060364 | 0.84 | EGLN1 (0.52) | EGLN1EGLN2 | |
| SCHEMBL15549041 | 0.84 | EGLN1 (0.75) | EGLN1EGLN2 | |
| SCHEMBL15549510 | 0.84 | EGLN1 (0.75) | EGLN1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |