Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL27737341 | 0.92 | GAA (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL21145050 | 0.90 | MEN1 (0.52) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL219044 | 0.89 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29207396 | 0.89 | KMT2A (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29076892 | 0.86 | KMT2A (0.55) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28223895 | 0.86 | KDM4E (0.55) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Acetic Acid SCHEMBL10707147 | 0.86 | MEN1 (0.63) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28386226 | 0.86 | MEN1 (0.55) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Acetic Acid SCHEMBL10708681 | 0.86 | MEN1 (0.63) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Acetic Acid SCHEMBL28048691 | 0.86 | KDM4E (0.63) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |
| CN-1631884-A | Process for preparing dimethomoph | LI ZEFANG (CN) | 2005-06-29 | — | — | CN | disclosed |