Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 14/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929898 | 1.00 | GBA1 (0.35) | GBA1EGLN1OGARETPDE4A | |
| SCHEMBL23929906 | 0.88 | HPGD (0.38) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929908 | 0.88 | HPGD (0.38) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929954 | 0.87 | EGLN1 (0.36) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929953 | 0.87 | EGLN1 (0.36) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929910 | 0.86 | GBA1 (0.37) | GBA1PDE4A | |
| SCHEMBL23929912 | 0.86 | GBA1 (0.37) | GBA1PDE4A | |
| SCHEMBL23957687 | 0.86 | GBA1 (0.39) | GBA1EGLN1RET | |
| SCHEMBL23930010 | 0.86 | GBA1 (0.39) | GBA1EGLN1RET | |
| SCHEMBL30175285 | 0.86 | GBA1 (0.39) | GBA1EGLN1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |