Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929906 | 1.00 | HPGD (0.38) | HPGDTSHRHTTHSD17B10GBA1 | |
| SCHEMBL23929898 | 0.88 | GBA1 (0.35) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929953 | 0.88 | EGLN1 (0.36) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929954 | 0.88 | EGLN1 (0.36) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23929900 | 0.88 | GBA1 (0.35) | GBA1EGLN1OGAPANK3 | |
| SCHEMBL23957686 | 0.82 | KMT2A (0.44) | HPGDGBA1EGLN1OGAPANK3 | |
| SCHEMBL30257935 | 0.79 | IRAK4 (0.31) | EGLN1 | |
| SCHEMBL23929959 | 0.78 | OGA (0.47) | HSD17B10GBA1OGAPANK3ALDH1A1 | |
| SCHEMBL23929957 | 0.78 | OGA (0.47) | HSD17B10GBA1OGAPANK3ALDH1A1 | |
| SCHEMBL23930009 | 0.78 | GBA1 (0.41) | GBA1OGANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |