Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929914 | 1.00 | GCG (0.35) | GCGGCGRHDAC3NCOR1HDAC1 | |
| SCHEMBL30175342 | 1.00 | GCG (0.35) | GCGGCGRHDAC3NCOR1HDAC1 | |
| SCHEMBL23929910 | 0.78 | GBA1 (0.37) | GCGGCGRHDAC3NCOR1HDAC1 | |
| SCHEMBL23929912 | 0.78 | GBA1 (0.37) | GCGGCGRHDAC3NCOR1HDAC1 | |
| SCHEMBL5641626 | 0.68 | KCNH2 (0.35) | — | |
| SCHEMBL21877327 | 0.66 | MTOR (0.32) | GCGR | |
| SCHEMBL23929898 | 0.66 | GBA1 (0.35) | — | |
| SCHEMBL23929900 | 0.66 | GBA1 (0.35) | — | |
| SCHEMBL24352271 | 0.66 | NOTUM (0.46) | GCGGCGR | |
| SCHEMBL23930019 | 0.65 | GCGR (0.44) | GCGGCGRHDAC3NCOR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |