Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929957 | 1.00 | OGA (0.47) | OGAPANK3GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23929961 | 0.78 | SMN1; SMN2 (0.33) | OGAKITPRCPMAPTALDH1A1 | |
| SCHEMBL30257772 | 0.78 | SMN1; SMN2 (0.33) | OGAKITPRCPMAPTALDH1A1 | |
| SCHEMBL23929906 | 0.78 | HPGD (0.38) | OGAPANK3GBA1ALDH1A1HSD17B10 | |
| SCHEMBL23929908 | 0.78 | HPGD (0.38) | OGAPANK3GBA1ALDH1A1HSD17B10 | |
| SCHEMBL23957686 | 0.78 | KMT2A (0.44) | OGAPANK3GBA1ALDH1A1LMNA | |
| SCHEMBL23930192 | 0.78 | GBA1 (0.41) | OGAGBA1MAPTALDH1A1LMNA | |
| SCHEMBL23930009 | 0.78 | GBA1 (0.41) | OGAGBA1MAPTALDH1A1LMNA | |
| SCHEMBL30175347 | 0.78 | GBA1 (0.41) | OGAGBA1MAPTALDH1A1LMNA | |
| SCHEMBL23929898 | 0.77 | GBA1 (0.35) | OGAPANK3GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |