Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30023884 | 1.00 | IKBKE (0.43) | IKBKETBK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30023029 | 0.86 | IKBKE (0.50) | IKBKETBK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL27143486 | 0.80 | LCK (0.43) | IKBKETBK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31413391 | 0.80 | LCK (0.43) | IKBKETBK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30023414 | 0.78 | IKBKE (0.41) | IKBKETBK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL31706474 | 0.77 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGSCN9A | |
| SCHEMBL23930271 | 0.76 | ALDH1A1 (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGLCK | |
| SCHEMBL25136506 | 0.76 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGSUV39H2 | |
| SCHEMBL24107476 | 0.74 | MAPK1 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL30263383 | 0.74 | MAPK1 (0.47) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-A | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2021213521-A1 | CBP/EP300 INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |