Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136482 | 0.74 | ALDH1A1 (0.30) | — | |
| SCHEMBL7565988 | 0.74 | — | — | |
| SCHEMBL9593909 | 0.73 | — | — | |
| SCHEMBL4559383 | 0.72 | ALDH1A1 (0.31) | DPP4 | |
| SCHEMBL527637 | 0.69 | — | — | |
| SCHEMBL528830 | 0.69 | — | — | |
| SCHEMBL87508 | 0.68 | — | — | |
| SCHEMBL9578971 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL331808 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL14312178 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338726-A | Hypotensive agents, antiulcer agents | ABBOTT LABORATORIES (US) | 1994-08-16 | — | — | US | claimed |
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | claimed |
| US-8921424-B2 | Histone deacetylase inhibitors, process for preparation and uses thereof | ZHEJIANG HISUN PHARMACEUTICAL CO. LTD. (CN) | 2014-12-30 | — | — | US | disclosed |
| EP-2208721-B1 | HISTONE DEACETYLASE INHIBITOR, COMPOSITION AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2013-12-25 | — | — | EP | disclosed |
| US-20110218221-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS, PROCESS FOR PREPARATION AND USES THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2011-09-08 | — | — | US | disclosed |
| EP-2208721-A1 | HISTONE DEACETYLASE INHIBITOR, COMPOSITION AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co. Ltd. (CN) | 2010-07-21 | — | — | EP | disclosed |
| WO-1994028012-A1 | HYDROXAMATE INHIBITORS OF ENDOTHELIN CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1994-12-08 | — | — | WO | disclosed |
| US-5338726-A | Hypotensive agents, antiulcer agents | ABBOTT LABORATORIES (US) | 1994-08-16 | — | — | US | disclosed |
| WO-1992013545-A1 | ENDOTHELIN CONVERTING ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1992-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218221-A1 | NOVEL HISTONE DEACETYLASE INHIBITORS, PROCESS FOR PREPARATION AND USES THEREOF | HDAC1, HDAC5, HDAC11 | DPP4 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.