SCHEMBL2393065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9890795	0.89	FGFR1 (0.46)	PTGS2MEN1LMNAMAPTKMT2A
	SCHEMBL9890794	0.84	HTT (0.43)	MEN1KMT2AHTTKDM4EFGFR1
	SCHEMBL2393913	0.81	MAPT (0.42)	ALDH1A1MEN1LMNAMAPTKMT2A
	SCHEMBL9890811	0.81	SLC6A4 (0.51)	SLC6A4SLC6A3PTGS2PTGS1ALDH1A1
	SCHEMBL2391431	0.81	SLC6A4 (0.45)	SLC6A4SLC6A3PTGS2PTGS1CASP3
	SCHEMBL9890687	0.73	SLC6A4 (0.55)	SLC6A4SLC6A3PTGS2PTGS1ALDH1A1
	SCHEMBL16731883	0.72	SLC6A4 (0.45)	SLC6A4SLC6A3PTGS2PTGS1CASP3
	SCHEMBL16409728	0.72	SLC6A4 (0.45)	SLC6A4SLC6A3PTGS2PTGS1CASP3
	SCHEMBL21590157	0.71	SLC6A4 (0.66)	SLC6A4SLC6A3PTGS2ALDH1A1HPGD
	SCHEMBL2391822	0.71	FGFR1 (0.44)	PTGS2ALDH1A1MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.