Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110486 | 1.00 | HTT (0.42) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL29212920 | 0.82 | HTT (0.39) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL21367479 | 0.82 | KDM4E (0.39) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL29472262 | 0.82 | KDM4E (0.59) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL14998245 | 0.82 | KDM4E (0.46) | HTTKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL22289639 | 0.82 | KDM4E (0.59) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL3587374 | 0.79 | KDM4E (0.42) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL14250219 | 0.78 | HTT (0.67) | HTTKDM4EALDH1A1MAPK1GLA | |
| SCHEMBL15893191 | 0.74 | MAPK1 (0.40) | HTTKDM4EALDH1A1MAPK1NSD2 | |
| SCHEMBL2824003 | 0.73 | IDH1 (0.37) | KDM4EALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743462-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012643-A1 | COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS | Tay Therapeutics Limited (GB) | 2025-01-16 | — | — | WO | disclosed |
| CN-115667244-B | 3-azabicycloalkyl derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-04-12 | — | — | CN | disclosed |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LG CHEM, LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LG CHEM, LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LG CHEM, LTD. (KR) | 2023-06-29 | — | — | US | disclosed |
| EP-4134366-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Lg Chem, Ltd. (KR) | 2023-02-15 | — | — | EP | disclosed |
| CN-115667244-A | 3-azabicycloalkyl derivatives and pharmaceutical compositions comprising the same | 株式会社LG化学 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021215765-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 엘지화학 (KR) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203008-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, ADCY1, ADCY7 | HTT 2025/4885KDM4E 2027/4885ALDH1A1 1538/4885 |
| US-20240067633-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | KHK, GCK, HK1 | HTT 776/4885KDM4E 911/4885ALDH1A1 710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.