Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.31 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540040 | 1.00 | SLC6A12 (0.31) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL26615175 | 1.00 | SLC6A12 (0.31) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL23930941 | 0.81 | GBA1 (0.31) | — | |
| SCHEMBL1924792 | 0.81 | SLC6A12 (0.35) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL1924790 | 0.81 | SLC6A12 (0.35) | SLC6A12SLC6A11SLC6A13 | |
| SCHEMBL3572337 | 0.80 | — | — | |
| SCHEMBL3572343 | 0.80 | — | — | |
| SCHEMBL3572340 | 0.80 | — | — | |
| SCHEMBL24126972 | 0.79 | NR1H2 (0.47) | — | |
| SCHEMBL30639947 | 0.79 | NR1H2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021215545-A1 | ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | WO | disclosed |