Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.33 |
| ▸ | MPG | P29372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | AGL | P35573 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LCT | P09848 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521636 | 1.00 | GBA1 (0.33) | GBA1MPGGAAMGAMAGL | |
| SCHEMBL2908778 | 0.86 | POLB (0.32) | — | |
| SCHEMBL2908775 | 0.86 | POLB (0.32) | — | |
| SCHEMBL3372261 | 0.86 | POLB (0.32) | — | |
| SCHEMBL9928687 | 0.83 | CHRNB2 (0.31) | GAA | |
| SCHEMBL6127398 | 0.83 | CHRNB2 (0.31) | GAA | |
| SCHEMBL6127402 | 0.83 | CHRNB2 (0.31) | GAA | |
| SCHEMBL3025369 | 0.82 | CYP46A1 (0.34) | GBA1GAA | |
| SCHEMBL15718081 | 0.82 | GBA1 (0.32) | GBA1GAA | |
| SCHEMBL3025364 | 0.82 | CYP46A1 (0.34) | GBA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2021215545-A1 | ANTICANCER COMBINATION THERAPY WITH N-(1-ACRYLOYL-AZETIDIN-3-YL)-2-((1H-INDAZOL-3-YL)AMINO)METHYL)-1H-IMIDAZOLE-5-CARBOXAMIDE INHIBITOR OF KRAS-G12C | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-10-28 | — | — | WO | disclosed |