Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238763 | 0.74 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL22289328 | 0.72 | HCAR2 (0.40) | GRM5 | |
| SCHEMBL16452810 | 0.71 | FSCN1 (0.42) | — | |
| SCHEMBL565646 | 0.70 | TDP1 (0.43) | — | |
| SCHEMBL2605779 | 0.69 | CDC25B (0.31) | — | |
| SCHEMBL16452809 | 0.69 | EGFR (0.36) | — | |
| SCHEMBL3770744 | 0.69 | LMNA (0.33) | — | |
| SCHEMBL17535285 | 0.69 | — | — | |
| SCHEMBL14910128 | 0.69 | POLB (0.36) | GRM5 | |
| SCHEMBL17947810 | 0.69 | CNR2 (0.32) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139306-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | F. Hoffmann-La Roche AG (CH) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214090-A1 | KV3 ENHANCERS FOR THE TREATMENT OF COGNITIVE DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2021-10-28 | — | — | WO | disclosed |