Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20396083 | 0.93 | USP30 (0.42) | USP30USP2SMN1; SMN2BUB1ALDH1A1 | |
| SCHEMBL23931390 | 0.90 | USP30 (0.41) | USP30USP2SMN1; SMN2NR1H2GPR183 | |
| SCHEMBL23931417 | 0.82 | USP30 (0.39) | USP30SCD5USP2SMN1; SMN2NR1H2 | |
| SCHEMBL19693266 | 0.81 | SCD5 (0.42) | USP30SCD5CYP11B2USP2SMN1; SMN2 | |
| SCHEMBL23584405 | 0.78 | USP30 (0.40) | USP30SCD5CYP11B2USP2SMN1; SMN2 | |
| SCHEMBL24753436 | 0.78 | USP30 (0.40) | USP30USP2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20396153 | 0.78 | USP30 (0.40) | USP30USP2SMN1; SMN2HDAC2NR1H2 | |
| SCHEMBL26134743 | 0.77 | SCD5 (0.42) | USP30SCD5CYP11B2HDAC2NR1H2 | |
| SCHEMBL26963358 | 0.75 | USP30 (0.38) | USP30SCD5CYP11B2USP2SMN1; SMN2 | |
| SCHEMBL16051476 | 0.75 | USP30 (0.40) | USP30SCD5CYP11B2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111408-A1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY AND HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2021216661-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216661-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |