Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933261 | 1.00 | EPHX1 (0.53) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL28826584 | 0.85 | EPHX1 (0.67) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3183223 | 0.79 | EPHX2 (0.60) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3183232 | 0.79 | EPHX2 (0.60) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL16064908 | 0.78 | GAA (0.66) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL16064910 | 0.78 | EPHX1 (0.63) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL7702219 | 0.77 | GAA (0.69) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL2716740 | 0.75 | EPHX1 (0.51) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL2718158 | 0.75 | EPHX1 (0.51) | EPHX1GAAKMT2ASMN1; SMN2LMNA | |
| SCHEMBL12218333 | 0.74 | GAA (0.65) | EPHX1GAAKMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |