Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.69 |
| ▸ | CHRND | Q07001 | 9/20 | 0.66 |
| ▸ | CHRNA1 | P02708 | 5/20 | 0.66 |
| ▸ | CHRNG | P07510 | 5/20 | 0.66 |
| ▸ | CHRNB1 | P11230 | 5/20 | 0.66 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.65 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.65 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933818 | 1.00 | GRIA1 (0.69) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL23933904 | 0.96 | GRIA1 (0.70) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL23933905 | 0.96 | GRIA1 (0.70) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10608759 | 0.86 | CTSS (0.67) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13063710 | 0.85 | CTSS (0.68) | GRIA1CTSSCTSK | |
| SCHEMBL13063712 | 0.85 | CTSS (0.68) | GRIA1CTSSCTSK | |
| SCHEMBL14517024 | 0.84 | CTSS (0.60) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL13063742 | 0.83 | CTSS (0.70) | CHRNB2CHRNB4CHRNA3CHRNA4CTSS | |
| SCHEMBL7384339 | 0.83 | CTSS (0.68) | CHRNDCHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL14598323 | 0.83 | CTSS (0.68) | CHRNDCHRNA1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217041-A1 | N-SUBSTITUTED ALPHA-AMINO AND ALPHA-HYDROXY CARBOXAMIDE DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |