Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.34 |
| ▸ | DRD2 | P14416 | 8/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934516 | 0.94 | IDO1 (0.33) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL23934723 | 0.93 | F10 (0.33) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL23934655 | 0.92 | IDO1 (0.37) | DRD3DRD2F10IDO1PDGFRB | |
| SCHEMBL23934512 | 0.89 | IDO1 (0.39) | DRD3DRD2HTR2AHTR1ADRD4 | |
| SCHEMBL23739656 | 0.85 | IDO1 (0.38) | IDO1ALDH1A1KDR | |
| SCHEMBL23739968 | 0.84 | IDO1 (0.37) | IDO1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL23739830 | 0.79 | IDO1 (0.36) | IDO1ALDH1A1KDR | |
| SCHEMBL23739523 | 0.78 | IDO1 (0.36) | IDO1ALDH1A1KDR | |
| SCHEMBL24572202 | 0.77 | POLB (0.35) | MEN1ALDH1A1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL23739667 | 0.77 | POLB (0.35) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896062-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-10-20 | — | — | EP | disclosed |