Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670683 | 0.84 | AHR (0.47) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL4670686 | 0.84 | AHR (0.47) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL25645153 | 0.83 | GRIN2D (0.50) | CYP1A2CYP2A6RELAMAOALMNA | |
| SCHEMBL4672666 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL20691469 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL4672669 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL4670685 | 0.80 | SMN1; SMN2 (0.54) | CYP1A2CYP2A6NQO2CHRM5MAOB | |
| SCHEMBL4670681 | 0.80 | SMN1; SMN2 (0.54) | CYP1A2CYP2A6NQO2CHRM5MAOB | |
| SCHEMBL2651407 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 | |
| SCHEMBL31499212 | 0.79 | KDM4E (0.61) | CYP1A2CYP2A6CYP19A1NQO2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323969-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKSCI INC. (CA) | 2021-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323969-A1 | FUSED TRIAZOLO-PYRIMIDINE COMPOUNDS HAVING USEFUL PHARMACEUTICAL APPLICATION | PIKFYVE, PIP4K2B, PIP4K2A | CYP1A2 4442/4885CYP2A6 4128/4885CYP19A1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.